Histopathological and Hematological studies on the effect of Cephalosporin in Treatment of Nile tilapia (Oreochromas niloticus) infected with Aeromonas hydrophila

Document Type : Original Article

Authors

1 Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University

2 Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt

3 Department of Pharmacology, Faculty of Vet. Medicine, Suez Canal university

Abstract

This study was conducted to investigate the curative effect of cefquinome against Aeromonas hydrophila in Nile tilapia and the effect of hematological and histopathological findings. One hundred and thirty-five Nile tilapia fish were used and divided into 3 equal groups. 1st group (GP) served as a negative control, 2nd GP was positive and infected with A. hydrophila while 3rd GP was infected group and treated with Cefquinome. The clinical signs improved in 3rd GP compared to 2nd GP and the mortality was decreased from 66.6 % in 2nd GP to 17.7 % in 3rd GP. Cefquinome treatment showed an improvement in all hematological parameters and histopathological findings of experimentally infected Nile tilapia in a time-dependent manner. It could be concluded that cefquinome is effective in treatment Nile tilapia fish against Aeromonas hydrophila infectioin with marked improvement in the health status and histopathological as well as hematological findings.

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