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Arafat, A., Kilany, O., Abdel-Rahman, H. (2021). The Potential Hypolipidemic Effect of Pomegranate Peel and Licorice Extracts in Rats. Suez Canal Veterinary Medical Journal. SCVMJ, 26(2), 411-429. doi: 10.21608/scvmj.2021.217937
Asmaa Arafat; Omnia Kilany; Haidy Abdel-Rahman. "The Potential Hypolipidemic Effect of Pomegranate Peel and Licorice Extracts in Rats". Suez Canal Veterinary Medical Journal. SCVMJ, 26, 2, 2021, 411-429. doi: 10.21608/scvmj.2021.217937
Arafat, A., Kilany, O., Abdel-Rahman, H. (2021). 'The Potential Hypolipidemic Effect of Pomegranate Peel and Licorice Extracts in Rats', Suez Canal Veterinary Medical Journal. SCVMJ, 26(2), pp. 411-429. doi: 10.21608/scvmj.2021.217937
Arafat, A., Kilany, O., Abdel-Rahman, H. The Potential Hypolipidemic Effect of Pomegranate Peel and Licorice Extracts in Rats. Suez Canal Veterinary Medical Journal. SCVMJ, 2021; 26(2): 411-429. doi: 10.21608/scvmj.2021.217937

The Potential Hypolipidemic Effect of Pomegranate Peel and Licorice Extracts in Rats

Article 12, Volume 26, Issue 2, December 2021, Page 411-429  XML
Document Type: Original Article
DOI: 10.21608/scvmj.2021.217937
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Authors
Asmaa Arafat* 1; Omnia Kilany2; Haidy Abdel-Rahman2
1Free Veterinarian
2Department of Clinical Pathology, Faculty of Veterinary Medicine, Suez Canal University
Abstract
Hyperlipidemia constitutes a major problem causing serious health problems. The current study was conducted to investigate the effect of Pomegranate peel (PC) and Licorice (LC) extracts as anti-hyperlipidemic agents in rats. Sixty male Wister rats were used in current study. They were divided into 6 groups; Group Ι: Control (C), Group ΙΙ: Pomegranate control (PC), Group ΙΙΙ: Licorice Control (LC), Group ΙѴ: Hyperlipidemia control (H), Group Ѵ: Hyperlipidemia pomegranate (HP), Group ѴΙ: Hyperlipidemia licorice (HL). Pomegranate was administrated 200 mg/kg body weight, while licorice was administrated 400 mg/kg body weight. All doses were given by oral gavage. The results showed that pomegranate peel and licorice extract significantly reversed the levels of serum lipid profile, glucose and hepatic damage markers, and antioxidant of hyperlipidemic rats. Histopathological examination of liver tissues was in concurrence with the biochemical results. It is logical to consider that the antihyperlipidemic and antioxidative properties of pomegranate and licorice are mechanistically achieved. So, pomegranate and licorice could be used as protective agents against hyperlipidemia and subsequent resulted metabolic disorders.
Keywords
Hyperlipidemia; pomegranate; licorice; lipid profile; liver; rats
Main Subjects
Clinical Pathology
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