Awad, M., Hassan, M., Saleh, S., Abuzeid, S., Hendawy, H. (2016). Evaluation of Polysulphated Glycoaaminoglycan and Dexaphenylarthrite in Treatment of Induced Tendonitis in Donkeys. Suez Canal Veterinary Medical Journal. SCVMJ, 21(2), 67-81. doi: 10.21608/scvmj.2016.62655
Mohamed Awad; Mohsen Hassan; Sherief Saleh; Saber Abuzeid; Hanan Hendawy. "Evaluation of Polysulphated Glycoaaminoglycan and Dexaphenylarthrite in Treatment of Induced Tendonitis in Donkeys". Suez Canal Veterinary Medical Journal. SCVMJ, 21, 2, 2016, 67-81. doi: 10.21608/scvmj.2016.62655
Awad, M., Hassan, M., Saleh, S., Abuzeid, S., Hendawy, H. (2016). 'Evaluation of Polysulphated Glycoaaminoglycan and Dexaphenylarthrite in Treatment of Induced Tendonitis in Donkeys', Suez Canal Veterinary Medical Journal. SCVMJ, 21(2), pp. 67-81. doi: 10.21608/scvmj.2016.62655
Awad, M., Hassan, M., Saleh, S., Abuzeid, S., Hendawy, H. Evaluation of Polysulphated Glycoaaminoglycan and Dexaphenylarthrite in Treatment of Induced Tendonitis in Donkeys. Suez Canal Veterinary Medical Journal. SCVMJ, 2016; 21(2): 67-81. doi: 10.21608/scvmj.2016.62655
Evaluation of Polysulphated Glycoaaminoglycan and Dexaphenylarthrite in Treatment of Induced Tendonitis in Donkeys
1Dept of Surgery, Anesthesiology and Radiology, Fac. Vet. Med., Suez Canal Univ.
2*Dept of Biochemistry ,Fac. Vet. Med., Suez Canal Univ.
3Dept of Anatomy and Embryology; Fac. Vet. Med., Suez Canal Univ.
4Dept of Surgery, Anesthesiology and Radiology, Fac. Vet. Med., Suez Canal Univ.
Abstract
The study was carried out in the superficial digital flexor tendon (SDFT) of the right forelimb of nine clinically apparently donkeys for evaluation the efficacy of Polysulfated Glycosaminoglycan (PSGAG) and Dexaphenylarthrite in treatment of artificial induced tendonitis. To achieve this goal, clinical, ultrasonography, biochemical and histopathological examinations were concluded. Tendonitis of the SDFT was induced by using bacterial collagenase enzyme from Clostridium histolyticum. Donkeys were classified into three groups. Group Ι (after induction of tendonitis they left as control group= 3 donkeys). Group ΙΙ, 3 days after induction of tendonitis, they received five IM injections of 5ml PSGAG (100 mg/ml) every four days. Group ΙΙΙ, 3 days after induction of tendonitis, they received Dexaphenylarthrite in a dose of 20 ml/day for the first two days followed by 10 ml/day for the other three days. From this study, it can be concluded that PSGAG had beneficial effects in treatment of artificial induced tendonitis in donkeys rather than Dexaphenylartrite based on clinical, ultrasonography, biochemical and histopathological findings.
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