Home Articles List Article Information
Suez Canal Veterinary Medical Journal. SCVMJ
Journal Archive
Volume Volume 30 (2025)
Volume Volume 29 (2024)
Volume Volume 28 (2023)
Volume Volume 27 (2022)
Volume Volume 26 (2021)
Volume Volume 25 (2020)
Volume Volume 24 (2019)
Volume Volume 23 (2018)
Volume Volume 22 (2017)
Volume Volume 21 (2016)
Volume Volume 20 (2015)
Volume Volume 19 (2014)
Volume Volume 18 (2013)
El-shahedy, M., Abdel Fatah, S., S., S., M., G. (2015). Immunostimulant Activity of Levamisole to Polyvalent FMD Vaccine in Buffaloes. Suez Canal Veterinary Medical Journal. SCVMJ, 20(2), 449-461. doi: 10.21608/scvmj.2015.64651
Mohamed El-shahedy; Shaira Abdel Fatah; Salem S.; Gamal M.. "Immunostimulant Activity of Levamisole to Polyvalent FMD Vaccine in Buffaloes". Suez Canal Veterinary Medical Journal. SCVMJ, 20, 2, 2015, 449-461. doi: 10.21608/scvmj.2015.64651
El-shahedy, M., Abdel Fatah, S., S., S., M., G. (2015). 'Immunostimulant Activity of Levamisole to Polyvalent FMD Vaccine in Buffaloes', Suez Canal Veterinary Medical Journal. SCVMJ, 20(2), pp. 449-461. doi: 10.21608/scvmj.2015.64651
El-shahedy, M., Abdel Fatah, S., S., S., M., G. Immunostimulant Activity of Levamisole to Polyvalent FMD Vaccine in Buffaloes. Suez Canal Veterinary Medical Journal. SCVMJ, 2015; 20(2): 449-461. doi: 10.21608/scvmj.2015.64651

Immunostimulant Activity of Levamisole to Polyvalent FMD Vaccine in Buffaloes

Article 32, Volume 20, Issue 2, December 2015, Page 449-461  XML PDF (1021.43 K)
Document Type: Original Article
DOI: 10.21608/scvmj.2015.64651
View on SCiNiTO View on SCiNiTO
Authors
Mohamed El-shahedy1; Shaira Abdel Fatah1; Salem S.2; Gamal M.* 2
1Department of Virology, Faculty of Veterinary Medicine, Suez Canal University
2Institute of Animal Health Research DokKi Giza
Abstract
In Egypt, many challenges facing eradication strategy of FMD concerning the short term immunity induced by inactivated polyvalent FMD vaccine. The aim of the study was directed to ascertain whether post vaccination antibodies against FMDV in buffaloes could be enhanced by administration with levamisole. To achieve the goal, 24 buffaloes were divided into 4 groups, G1 is non vaccinated non adjuvanted group, G2 is vaccine control group, G3 is simultaneously FMD vaccinated and levamisole stimulated group and G4 is FMD vaccinated 7 days after levamisole stimulation. Blood samples were examined for 16 succesive weeks post vaccination for FMD antibodies to serotypes O, A and SAT-2 by ELISA test. The results revealed that animalssimultinously vaccinated and treated with levamisole was higher than the group adjuvinated with levamisole 7 days before FMD vaccination. Levamisole has stimulant effect on the vaccinalimmunity of buffaloes to FMD serotypes O, A and SAT2. Antibody titers of FMD in animal groups were parallel in each group with a high titer in serotype A than O and SAT2. Further investigations are needed to explore the effect of levamisole on cell mediated immune response and challenge test in buffaloes.
Keywords
Immunostimulant; Levamisole; FMD Vaccine; buffaloes
Main Subjects
Virology
Statistics
Article View: 202
PDF Download: 487